2009年3月19日星期四

用DTI证明智力是遗传的

Medgadget报道,UCLA(加州大学洛杉矶分校)对同卵双胞胎和异卵双胞胎来进行DTI脑神经连接的扫描,发现行为遗传学早就发现的事实(或者从神经科学上得到更多证据):智力很大程度上来自遗传。当然,它并没有说具体是哪种智力(按照韦克斯乐量表来分,是操作智力还是言语智力;还有晶体智力、流体智力。ORZ,智力和记忆一样复杂。)

Source: Here

HARDI Scanner Says Intelligence Is Inherited

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Using a HARDI (High-Angular Resolution Diffusion Imaging) scanner to visualize brain myelin composition, a group of researchers from UCLA confirmed what everyone has already known. Your coworkers are doofuses because they were born to dumb parents.

UCLA explains how some of us are just better than others:



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Genes appear to influence intelligence by determining how well nerve axons are encased in myelin — the fatty sheath of "insulation" that coats our axons and allows for fast signaling bursts in our brains. The thicker the myelin, the faster the nerve impulses.

Thompson [Paul Thompson, UCLA neurology professor] and his colleagues scanned the brains of 23 sets of identical twins and 23 sets of fraternal twins. Since identical twins share the same genes while fraternal twins share about half their genes, the researchers were able to compare each group to show that myelin integrity was determined genetically in many parts of the brain that are key for intelligence. These include the parietal lobes, which are responsible for spatial reasoning, visual processing and logic, and the corpus callosum, which pulls together information from both sides of the body.

The researchers used a faster version of a type of scanner called a HARDI (high-angular resolution diffusion imaging) — think of an MRI machine on steroids — that takes scans of the brain at a much higher resolution than a standard MRI. While an MRI scan shows the volume of different tissues in the brain by measuring the amount of water present, HARDI tracks how water diffuses through the brain's white matter — a way to measure the quality of its myelin.

"HARDI measures water diffusion," said Thompson, who is also a member of the UCLA Laboratory of Neuro-Imaging. "If the water diffuses rapidly in a specific direction, it tells us that the brain has very fast connections. If it diffuses more broadly, that's an indication of slower signaling, and lower intelligence."

"So it gives us a picture of one's mental speed," he said.

Because the myelination of brain circuits follows an inverted U-shaped trajectory, peaking in middle age and then slowly beginning to decline, Thompson believes identifying the genes that promote high-integrity myelin is critical to forestalling brain diseases like multiple sclerosis and autism, which have been linked to the breakdown of myelin.

Press release: Study gives more proof that intelligence is largely inherited.

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