他们发现通过口服某种叫做心得安(propranolol,用于心血管疾病)的药物的恐惧症患者24小时后再次记忆唤起时恐惧情绪不会再出现。
MIT技术评论有详细的实验过程。
这类药物统称为Emoceuticals(可以看Brainwaves的博客)。
这里还有些对这类药物的伦理批评。
当然,筒子们不用过于害怕,因为这里有英文说明这其实不是删除记忆的药物。作者指出这种药暂时删除的是与蜘蛛记忆有关的害怕反应,而不是蜘蛛记忆本身,因此更应该像《新科学家》杂志那样将其称作“抗恐怖症药”(anti-phobia drug)。所以说白了,这不是cogniceutical,而是emoceutical。它对认知及记忆没有任何影响。
这个传播很有意思,也说明脑科学、心理学的结论很容易像20世纪初的时候“优生学运动”那样被误用。
摘要:
Brief Communication abstract
Nature Neuroscience
Published online: 15 February 2009 | doi:10.1038/nn.2271
Beyond extinction: erasing human fear responses and preventing the return of fear
Merel Kindt1, Marieke Soeter1 & Bram Vervliet1
Animal studies have shown that fear memories can change when recalled, a process referred to as reconsolidation. We found that oral administration of the -adrenergic receptor antagonist propranolol before memory reactivation in humans erased the behavioral expression of the fear memory 24 h later and prevented the return of fear. Disrupting the reconsolidation of fear memory opens up new avenues for providing a long-term cure for patients with emotional disorders.
- Department of Clinical Psychology, University of Amsterdam, Roetersstraat 15, 1018 WB Amsterdam, The Netherlands.
Correspondence to: Merel Kindt1 e-mail: m.kindt@uva.nl